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Double Marker Test – Purpose, Procedure, Normal Range & Cost

Category: Health | Published: August 30, 2025

Pregnancy is a special journey, but it also comes with the responsibility of ensuring both the mother and baby are healthy. Modern diagnostic tests help doctors detect potential complications early so that timely medical decisions can be taken. One such important screening during pregnancy is the Double Marker Test.

At Redcliffe Labs, you can easily book the Double Marker Test with free home sample collection, affordable pricing, and accurate results from NABL-certified labs.

What is the Double Marker Test?

The Double Marker Test is a prenatal blood screening test conducted during the first trimester of pregnancy (between 11 and 14 weeks). It is used to detect chromosomal abnormalities in the fetus, such as:

  • Down Syndrome (Trisomy 21)
  • Trisomy 18 (Edwards Syndrome)
  • Trisomy 13 (Patau Syndrome)

The test measures levels of two important markers in the mother’s blood:

  1. Free Beta-hCG (Human Chorionic Gonadotropin): A hormone produced during pregnancy.
  2. PAPP-A (Pregnancy-Associated Plasma Protein A): A protein produced by the placenta.

Abnormal levels of these markers can indicate chromosomal abnormalities or genetic disorders in the developing baby.

Why is the Double Marker Test Important?

  • Early Detection of Genetic Disorders: Helps assess the risk of chromosomal abnormalities in the fetus.
  • Safer Pregnancy Management: Allows doctors to suggest further diagnostic tests like NIPT (Non-Invasive Prenatal Testing), CVS (Chorionic Villus Sampling), or Amniocentesis if needed.
  • Informed Decisions: Gives expecting parents the knowledge to take timely medical advice.
  • Peace of Mind: Normal results reassure parents about the baby’s development.

Who Should Get the Double Marker Test?

While doctors may recommend it for all pregnant women, it is especially important for:

  • Women aged 35 years and above (higher risk of chromosomal issues).
  • Pregnant women with a family history of genetic disorders.
  • Mothers with previous abnormal pregnancies or miscarriages.
  • Women with exposure to infections, radiation, or harmful substances during early pregnancy.

How is the Double Marker Test Done?

The Double Marker Test is a simple blood test:

  1. A small blood sample is taken from the mother.
  2. The sample is analyzed in the lab for Free Beta-hCG and PAPP-A levels.
  3. The results are combined with ultrasound findings (NT Scan – Nuchal Translucency Test) for more accuracy.

It is a non-invasive and risk-free test for both mother and baby.

Normal Range of Double Marker Test

  • Free Beta-hCG:
  • High levels → May indicate a higher risk of Down syndrome.
  • Low levels → May indicate risk of Edwards syndrome or Patau syndrome.

    PAPP-A:

  • Low levels are associated with chromosomal abnormalities.
  • Since values vary depending on gestational age and individual health, doctors interpret results along with ultrasound scans.

Cost of Double Marker Test in India

The cost of the Double Marker Test in India usually ranges between ₹2,500 and ₹3,500.
At Redcliffe Labs, you get:

  • Affordable pricing with transparent charges
  • Free home sample collection
  • Accurate reports from NABL & ISO-certified labs
  • Reports available online within 24–48 hours

Why Choose Redcliffe Labs for Double Marker Test?

  • NABL-accredited labs ensuring accurate results
  • Free home sample collection across India
  • Quick digital reports within 24–48 hours
  • Affordable packages for pregnancy care
  • Expert guidance for further testing if needed

Conclusion

The Double Marker Test is a vital part of prenatal care that helps in early risk detection of genetic abnormalities in the fetus. It is simple, safe, and reliable.

If you are in your first trimester, consult your gynecologist about the test. With Redcliffe Labs, you can book the test online, get home sample collection, and receive accurate reports without any hassle.

Take the step towards a safe and healthy pregnancy—book your Double Marker Test with Redcliffe Labs today.